Antibacterial soap use impacts skin microbial communities in rural Madagascar

Autor: Sarah C. Windsor, Julie E. Horvath, Charles L. Nunn, James J. Yu, Melissa B. Manus, Olaf Mueller
Jazyk: angličtina
Rok vydání: 2018
Předmět:
0301 basic medicine
Skin Physiology
Male
Rural Population
Time Factors
medicine.medical_treatment
Beta diversity
Biodiversity
lcsh:Medicine
Medicine and Health Sciences
lcsh:Science
Skin
education.field_of_study
Multidisciplinary
integumentary system
Ecology
Antimicrobials
Pharmaceutics
Microbiota
Drugs
Agriculture
Genomics
Middle Aged
Anti-Bacterial Agents
Chemistry
Shannon Index
Medical Microbiology
Physical Sciences
Anatomy
Integumentary System
Research Article
Hand Disinfection
Antibacterial soap
Adult
Ecological Metrics
Adolescent
030106 microbiology
Population
Microbial Genomics
Biology
Soaps
Microbiology
03 medical and health sciences
Young Adult
Dose Prediction Methods
Environmental health
Microbial Control
medicine
Genetics
Madagascar
Humans
education
Aged
Pharmacology
Bacteria
Dose-Response Relationship
Drug
lcsh:R
Ecology and Environmental Sciences
Chemical Compounds
Organisms
Species diversity
Biology and Life Sciences
Species Diversity
030104 developmental biology
Antibacterials
Alpha diversity
lcsh:Q
Salts
Species richness
Microbiome
Rural area
Zdroj: PLoS ONE
PLoS ONE, Vol 13, Iss 8, p e0199899 (2018)
ISSN: 1932-6203
Popis: The skin harbors diverse communities of microorganisms, and alterations to these communities can impact the effectiveness of the skin as a barrier to infectious organisms or injury. As the global availability and adoption of antibacterial products increases, it is important to understand how these products affect skin microbial communities of people living in rural areas of developing countries, where risks of infection and injury often differ from urban populations in developed countries. We investigated the effect of antibacterial soap on skin microbial communities in a rural Malagasy population that practices subsistence agriculture in the absence of electricity and running water. We quantified the amount of soap used by each participant and obtained skin swab samples at three time points: prior to soap use, immediately after one week of soap use, and two weeks after soap use was discontinued. Soap use did not significantly impact ecological measures of diversity and richness (alpha diversity). However, the amount of soap used was a predictor of community-level change (beta diversity), with changes persisting for at least two weeks after subjects stopped using soap. Our results indicate that the overall species richness of skin microbial communities may be resistant to short-term use of antibacterial soap in settings characterized by regular contact with the natural environment, yet these communities may undergo shifts in microbial composition. Lifestyle changes associated with the use of antibacterial soap may therefore cause rapid alterations in skin microbial communities, with the potential for effects on skin health.
Databáze: OpenAIRE
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