Structural characterization and immunological activity of polysaccharides from the tuber of Bletilla striata
| Autor: | Jinye Bai, Shao-Wei Han, Ruo-Fei Li, Xinzhu Qi, Shuai Li, Qi Hou, Bao-Song Cui, Yi-Rui Wang, Xian-Jie Ma, Mingbao Lin |
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| Rok vydání: | 2019 |
| Předmět: |
Molar
Mannose Spleen Thymus Gland 02 engineering and technology Polysaccharide Methylation Biochemistry Leukocyte Count Mice 03 medical and health sciences chemistry.chemical_compound fluids and secretions stomatognathic system Polysaccharides Structural Biology Bletilla striata medicine Animals Immunologic Factors Orchidaceae Molecular Biology 030304 developmental biology chemistry.chemical_classification 0303 health sciences Molecular mass biology Plant Extracts Chemistry Monosaccharides General Medicine 021001 nanoscience & nanotechnology biology.organism_classification Molecular Weight Plant Tubers medicine.anatomical_structure Composition (visual arts) 0210 nano-technology |
| Zdroj: | International Journal of Biological Macromolecules. 122:628-635 |
| ISSN: | 0141-8130 |
| Popis: | Two water-soluble polysaccharides, BSP-1 and BSP-2, were extracted and purified from the tuber of Bletilla striata. The molecular weights of BSP-1 and BSP-2 were 83.54 kDa and 12.60 kDa, respectively. The composition and proportion of BSP-1 and BSP-2 were mannose and glucose in molar ratios of 4.0:1.0 and 3.0:1.0 respectively. The two polysaccharides had a linear backbone, consisting mainly of repeating β‑1,4‑linked d ‑mannosyl residues and β‑1,4‑linked d ‑glucosyl residues. BSP-1 exhibited immunomodulatory effects by increasing the thymus and spleen indices of immunocompromised model mice. |
| Databáze: | OpenAIRE |
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