Ecological and evolutionary dynamics of a model facultative pathogen: Agrobacterium and crown gall disease of plants
| Autor: | Clay Fuqua, Ian S. Barton, Thomas G. Platt |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
media_common.quotation_subject Ecology (disciplines) 030106 microbiology Context (language use) Disease Biology Microbiology Competition (biology) Article 03 medical and health sciences Plant Tumors Gall Evolutionary dynamics Ecology Evolution Behavior and Systematics media_common Facultative Ecology fungi Plants Biological Evolution 030104 developmental biology Agrobacterium tumefaciens Biofilms Evolutionary ecology Plasmids |
| Zdroj: | Environmental microbiology. 20(1) |
| ISSN: | 1462-2920 |
| Popis: | Many important pathogens maintain significant populations in highly disparate disease and non-disease environments. The consequences of this environmental heterogeneity in shaping the ecological and evolutionary dynamics of these facultative pathogens are incompletely understood. Agrobacterium tumefaciens, the causative agent for crown gall disease of plants has proven a productive model for many aspects of interactions between pathogens and their hosts and with other microbes. In this review, we highlight how this past work provides valuable context for the use of this system to examine how heterogeneity and transitions between disease and non-disease environments influence the ecology and evolution of facultative pathogens. We focus on several features common among facultative pathogens, such as the physiological remodelling required to colonize hosts from environmental reservoirs and the consequences of competition with host and non-host associated microbiota. In addition, we discuss how the life history of facultative pathogens likely often results in ecological tradeoffs associated with performance in disease and non-disease environments. These pathogens may therefore have different competitive dynamics in disease and non-disease environments and are subject to shifting selective pressures that can result in pathoadaptation or the within-host spread of avirulent phenotypes. |
| Databáze: | OpenAIRE |
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