Mucinous adenocarcinoma of the lung in association with congenital pulmonary airway malformation
| Autor: | Bahig M. Shehata, Christina A. Stockwell, Louis Rapkin, John C. Bleacher, Ryan J. Summers |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Pathology
medicine.medical_specialty Lung Neoplasms Pleuropulmonary blastoma Malignancy medicine.disease_cause Diagnosis Differential Cystic Adenomatoid Malformation of Lung Congenital Bronchoscopy medicine Adenocarcinoma of the lung Humans Rhabdomyosarcoma Child Pneumonectomy Lung business.industry Congenital pulmonary airway malformation General Medicine respiratory system medicine.disease Adenocarcinoma Mucinous respiratory tract diseases medicine.anatomical_structure Pediatrics Perinatology and Child Health Adenocarcinoma Surgery Female KRAS business Tomography X-Ray Computed Precancerous Conditions |
| Zdroj: | Journal of pediatric surgery. 45(11) |
| ISSN: | 1531-5037 |
| Popis: | Congenital pulmonary airway malformation (CPAM) is a rare developmental abnormality of the lung that has been associated with the presence of rhabdomyosarcoma, pleuropulmonary blastoma, and most commonly bronchioalveolar carcinoma (BAC) of the lung. Here, we report the case of an 8-year-old patient who developed KRAS mutation positive stage IV mucinous adenocarcinoma of the lung in association with CPAM. This case reflects the previously recognized progression of CPAM to malignancy and suggests that BAC arising in CPAM may take a more aggressive course than previously recognized. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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