The Synthesis of Dicationic Extended Bis-Benzimidazoles
| Autor: | Zhijan Kang, Christine C. Dykstra, David W. Boykin |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Cyclopropanes
Stereochemistry Pharmaceutical Science amidines Bacillus subtilis Alkenes Article DIBAL reduction Analytical Chemistry Cyclopropane lcsh:QD241-441 chemistry.chemical_compound lcsh:Organic chemistry Nitriles Drug Discovery Escherichia coli Organic chemistry Physical and Theoretical Chemistry Pentamidine benzimidazoles biology Chemistry Organic Chemistry biology.organism_classification Anti-Bacterial Agents Chemistry (miscellaneous) Molecular Medicine |
| Zdroj: | Molecules, Vol 9, Iss 3, Pp 158-163 (2004) Molecules Volume 9 Issue 3 Pages 158-163 |
| ISSN: | 1420-3049 |
| DOI: | 10.3390/90300158 |
| Popis: | The synthesis of extended dicationic bis-benzimidazoles starting from trans‑1,2-bis(4-cyanophenyl)ethene and trans‑1,2-bis(4-cyanophenyl)cyclopropane is reported. The target diamidines show significant in vitro activity against B. subtilis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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