| Autor: |
Rachael Kermond, Andrew Mallett, Hugh McCarthy |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Pediatric nephrology (Berlin, Germany). |
| ISSN: |
1432-198X |
| Popis: |
Kidney tubules are responsible for the preservation of fluid, electrolyte and acid-base homeostasis via passive and active mechanisms. These physiological processes can be disrupted by inherited or acquired aetiologies. The net result is a tubulopathy. It is important to make a prompt and accurate diagnosis of tubulopathies in children and young adults. This allows timely and appropriate management, including disease-specific therapies, and avoids complications such as growth failure. Tubulopathies can present with a variety of non-specific clinical features which can be diagnostically challenging. In this review, we build from this common anatomical and physiological understanding to present a tangible appreciation of tubulopathies as they are likely to be clinically encountered among affected children and young adults. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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Full text from SpringerLink