Effects of prenatal cocaine/polydrug exposure on substance use by age 15
| Autor: | Adelaide Lang, Lynn T. Singer, Miaoping Wu, Meeyoung O. Min, Sonia Minnes, Susan Yoon |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male Injury control Adolescent Accident prevention Substance-Related Disorders Physiology Poison control Toxicology Article Cocaine-Related Disorders Young Adult Pregnancy Risk Factors mental disorders Injury prevention medicine Humans Pharmacology (medical) Longitudinal Studies Prospective Studies Pharmacology business.industry Age Factors Prenatal cocaine exposure medicine.disease Psychiatry and Mental health Child Preschool Prenatal Exposure Delayed Effects Cocaine use Female Medical emergency Self Report Substance use business Follow-Up Studies |
| Zdroj: | Drug and alcohol dependence. 134 |
| ISSN: | 1879-0046 |
| Popis: | Examined effects of prenatal cocaine exposure (PCE) on tobacco, alcohol, marijuana and cocaine use by age 15.Adolescent (n=358; 183 PCE, 175 non-prenatally cocaine exposed; NCE) drug use was assessed using urine, hair, and/or blood spot samples and self-report (Youth Risk Behavior Surveillance System; YRBSS) at ages 12 and 15. Logistic regression assessed effects of PCE on drug use controlling for other drug exposures, environment and blood lead levels (BLL).Adjusted percentages of drug use (PCE vs. NCE) were: tobacco 35% vs. 26% (p.04), marijuana 33% vs. 23% (p.04), alcohol 40% vs. 35% (p.01), and any drugs 59% vs. 50% (p.005). PCE adolescents were twice as likely to use tobacco (OR=2.02, 95% CI=1.05-3.90, p.04), 2.2 times more likely to use alcohol (OR=2.16, 95% CI=1.21-3.87, p.01) and 1.8 times more likely to use marijuana (OR=1.81, 95% CI=1.02-3.22, p.04) than NCE adolescents. A race-by-cocaine-exposure interaction (p.01) indicated PCE non-African American adolescents had greater probability of tobacco use (65%) than NCE non-African American youth (21%). PCE was associated with any drug use (OR=2.16, CI=1.26-3.69, p.005), while higher BLL predicted alcohol use (p.001). Violence exposure was a predictor of tobacco (p.002), marijuana (p.0007) and any drug (p.04).PCE and exposure to violence increased the likelihood of tobacco, marijuana or any drug use by age 15, while PCE and higher early BLL predicted alcohol use. Prevention efforts should target high risk groups prior to substance use initiation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect