Thyroid function in leukaemia patients after allogeneic bone marrow transplantation
| Autor: | M. Frölich, B.M. Goslings, M.M. de Planque, A.E. Meinders |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
Adult
Male endocrine system medicine.medical_specialty endocrine system diseases Cyclophosphamide Adolescent Clinical Biochemistry Thyroid Gland Thyrotropin Biochemistry Gastroenterology Sex Factors Internal medicine medicine Humans Bone Marrow Transplantation Leukemia business.industry Biochemistry (medical) Thyroid General Medicine Total body irradiation medicine.disease Surgery Transplantation medicine.anatomical_structure Female Bone marrow Thyroid function Complication business hormones hormone substitutes and hormone antagonists Whole-Body Irradiation medicine.drug |
| Zdroj: | Clinica chimica acta; international journal of clinical chemistry. 165(2-3) |
| ISSN: | 0009-8981 |
| Popis: | The thyroid function of 29 patients who underwent allogeneic bone marrow transplantation preceded by total body irradiation was followed closely during four weeks after transplantation. Twenty patients showed a marked decrease of T3 and TSH levels, whereas T4 fluctuated. Long-term follow up from three to five years of the surviving 16 patients revealed a restoration of the T3 levels to normal, a slight increase in T4 levels and a doubling of the TSH levels. This indicates the necessity of a higher pituitary drive to maintain euthyroidism. One patient developed hypothyroidism. |
| Databáze: | OpenAIRE |
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