The cost-effectiveness of 18FDG-PET in selecting patients with suspicion of recurrent laryngeal carcinoma after radiotherapy for direct laryngoscopy
| Autor: | C. René Leemans, Addy C. G. van Hooren, Remco de Bree, Otto S. Hoekstra, Carin A. Uyl-de Groot, Jolijn Brouwer |
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| Přispěvatelé: | Otolaryngology / Head & Neck Surgery, Epidemiology and Data Science, CCA - Disease profiling, Radiology and nuclear medicine |
| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty 18FDG-PET Cost effectiveness medicine.medical_treatment Cost-Benefit Analysis Laryngoscopy Sensitivity and Specificity Fluorodeoxyglucose F18 medicine Humans 18fdg pet Laryngeal Neoplasms Aged Aged 80 and over medicine.diagnostic_test Radiotherapy business.industry General Medicine Recurrent laryngeal carcinoma Middle Aged Recurrent Laryngeal Carcinoma Endoscopy Surgery Radiation therapy Otorhinolaryngology Positron-Emission Tomography Cost-effectiveness Female Neurosurgery Neoplasm Recurrence Local Radiopharmaceuticals business Head and Neck |
| Zdroj: | European Archives of Oto-Rhino-Laryngology van Hooren, A C G, Brouwer, J, de Bree, R, Hoekstra, O S, Leemans, C R & Uyl-de Groot, C A 2009, ' The cost-effectiveness of (18)FDG-PET in selecting patients with suspicion of recurrent laryngeal carcinoma after radiotherapy for direct laryngoscopy ', European Archives of Oto-Rhino-Laryngology, vol. 266, no. 9, pp. 1441-1448 . https://doi.org/10.1007/s00405-008-0878-3 European Archives of Oto-Rhino-Laryngology, 266(9), 1441-1448. Springer Verlag |
| ISSN: | 1434-4726 0937-4477 |
| Popis: | The aim of this study was to estimate the cost-effectiveness of (18)FDG-PET in the selection for direct laryngoscopy in patients with suspicion of recurrent laryngeal carcinoma after radiotherapy. The direct medical costs of 30 patients with suspicion of a recurrence were calculated from the first visit where suspicion was raised until one year after. A conventional strategy, in which all these patients underwent direct laryngoscopy, was compared to an (18)FDG-PET strategy in which only patients with a positive or equivocal (18)FDG-PET underwent direct laryngoscopy. A sensitivity analysis was performed to examine the influence of the type of camera and 'setting'. The mean costs of an (18)FDG-PET strategy were 399 euros less than a direct laryngoscopy strategy. The type of camera and setting had no influence. In patients with suspicion for recurrent laryngeal carcinoma after radiotherapy, (18)FDG-PET seems to be effective and less costly in selecting patients for direct laryngoscopy. |
| Databáze: | OpenAIRE |
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