Factors Affecting Survival in Congenital Diaphragmatic Hernia: A Prospective Study at a Tertiary Center
| Autor: | Tahereh Esmaeilnia Shirvany, Hosein Dalili, Fateme Nayeri, Azita Parvizizadeh, Maryam Ghavami-Adel, Mamak Shariat, Elahe Amini, Vafa Ghorbansabagh |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Pediatrics
medicine.medical_specialty Diaphragmatic hernia Survival business.industry Mortality rate lcsh:RJ1-570 lcsh:Surgery Congenital diaphragmatic hernia Predictive outcome lcsh:Pediatrics Peak inspiratory pressure lcsh:RD1-811 medicine.disease Pulmonary hypoplasia Pediatrics Perinatology and Child Health medicine Surgery Apgar score Prospective cohort study business Survival rate Congenital heart disease |
| Zdroj: | Journal of Neonatal Surgery, Vol 8, Iss 4 (2020) |
| ISSN: | 2226-0439 |
| Popis: | Background: The outcome of congenital diaphragmatic hernia depends on associated anomalies, degree of pulmonary hypoplasia, and hypertension. We evaluated the postnatal prognostic factors which can be used to predict the outcome.Methods: This study was conducted at a tertiary center (Vali-e-Asr Hospital, Imam Khomeini Complex, Tehran, Iran) during 2013-2019. The predictors of survival were evaluated.Results: A total of 49 infants with congenital diaphragmatic hernia were born during 2013-2019. The patients’ mean gestational age and weight at birth were 37.51±1.75 weeks and 2871±562 g, respectively. The mortality rate in patients with surgery (n = 41) was 31.3% and eight patients died before surgery. Mortality had significant relationships with five-minute Apgar score, peak inspiratory pressure before and after surgery, partial pressure of arterial oxygen (PaO2), and pH during first 24 hours after birth (p= 0.01, 0.001, and 0.01, respectively). The predicted and true survival rates in the patients were 66% and 52%, respectively (p= 0.001).Conclusion: Predicting survival rate after birth is remarkable but controversial. This estimate should not affect patient care and should only help parents in the process of decision-making. |
| Databáze: | OpenAIRE |
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