Validity of visceral adiposity estimates from DXA against MRI in Kuwaiti men and women

Autor: Anwar Mohammad, Alison Sleigh, Soren Brage, Kazem Behbehani, E De Lucia Rolfe, Nicholas J. Wareham, T Mohammad, Toomas Kivisild
Přispěvatelé: De Lucia Rolfe, Emanuella [0000-0003-3542-2767], Kivisild, Toomas [0000-0002-6297-7808], Wareham, Nicholas [0000-0003-1422-2993], Brage, Soren [0000-0002-1265-7355], Apollo - University of Cambridge Repository
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Nutrition & Diabetes
DOI: 10.17863/cam.4311
Popis: Objectives - The prevalence of obesity and diabetes in the Middle East is amongst the highest in the world. Valid measures of abdominal adiposity are essential to understanding the metabolic consequences of obesity. Dual-energy X-ray absorptiometry (DXA) is increasingly being utilised to assess body composition in population studies, and has recently been used to estimate visceral adipose tissue (VAT). The aim of this study was to determine the accuracy of DXA-derived VAT in a Middle Eastern population using magnetic resonance imaging (MRI) as the criterion measure. ${\bf Method:}$ VAT was estimated from abdominal DXA measures in 237 adult men (n=130) and women (n=107), aged 18-65 years, participating in the Kuwait Wellbeing Study. These estimates were compared to MRI measures of the corresponding anatomical region. The agreement between methods was assessed using Bland-Altman as well as correlation analysis. ${\bf Results:}$ Median MRI-VAT was 1148.5 (95% CI: 594.2-1734.6) cm$^3$ in men and 711.3 (95% CI: 395.5-1042.8) cm$^3$ in women. DXA estimates of VAT showed high correlations with corresponding MRI measures (r= 0.94 (p
This research was supported by funding from His Highness Shiekh Nasser Al-Mohammad Al-Sabah, the Dasman Diabetes Institute (RA-2010-001), and the Medical Research Council (MC_UU_12015/1 and MC_UU_12015/3).
Databáze: OpenAIRE