Fruit and vegetable intake and gastric cancer risk in a large United States prospective cohort study
| Autor: | A F Subar, Arthur Schatzkin, Neal D. Freedman, Christian C. Abnet, Michael F. Leitzmann, Albert R. Hollenbeck |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Male
Risk Cancer Research medicine.medical_specialty Risk Factors Stomach Neoplasms Internal medicine Vegetables Epidemiology medicine Humans Prospective Studies Prospective cohort study Aged Proportional Hazards Models Proportional hazards model business.industry Incidence Incidence (epidemiology) Hazard ratio Cancer Feeding Behavior Middle Aged medicine.disease United States Surgery Oncology Fruit Cohort Female business Cohort study |
| Zdroj: | Cancer Causes & Control. 19:459-467 |
| ISSN: | 1573-7225 0957-5243 |
| Popis: | Fruit and vegetable intake may protect against gastric cancer incidence. Results from case–control studies have indicated an inverse association, but results from cohort studies are inconsistent. We prospectively investigated the association in 490,802 participants of the NIH-AARP Diet and Health Study using Cox proportional hazards models adjusted for gastric cancer risk factors. We present hazard ratios (HR) and 95% confidence intervals (CI) per increase of one daily serving per 1,000 calories. During 2,193,751 person years, 394 participants were diagnosed with incident gastric cancer. We observed no significant associations between total fruit and vegetable intake (1.01, 0.95–1.08), fruit intake (1.04, 0.95–1.14), or vegetable intake (0.98, 0.88–1.08) and gastric cancer risk. Results did not vary by sex or anatomic subsite (cardia versus non-cardia). All 13 botanical subgroups examined had no significant associations with either anatomic sub-site. We did not observe significant associations between overall fruit and vegetable intake and gastric cancer risk in this large prospective cohort study. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink