Photobiomodulation Therapy in Bone Repair Associated with Bone Morphogenetic Proteins and Guided Bone Regeneration: A Histomorphometric Study
| Autor: | José Alcides Almeida de Arruda, Natália Costa Brasilino, Vanda Sanderana Macêdo Carneiro, Marleny Elizabeth Martinez Gerbi, Antonio Luiz Barbosa Pinheiro, Rebeca Ferraz de Menezes, Jéssica Meirinhos Miranda, Lara Marques Magalhães Moreno, Aldo Brugnera Junior |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Pathology medicine.medical_specialty Bone Regeneration Biomedical Engineering Bone healing Bone morphogenetic protein Random Allocation 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine medicine Animals Radiology Nuclear Medicine and imaging Femur Low-Level Light Therapy Rats Wistar Bone regeneration Guided Tissue Regeneration business.industry Membranes Artificial Surgical wound 030206 dentistry Rats Bone Morphogenetic Proteins Models Animal Cattle Lasers Semiconductor business |
| Zdroj: | Photomedicine and Laser Surgery. 36:581-588 |
| ISSN: | 1557-8550 |
| DOI: | 10.1089/pho.2017.4421 |
| Popis: | To evaluate the efficacy of photobiomodulation for bone repair of critical surgical wounds with implants of bone morphogenetic proteins (BMPs) and bovine biological membranes, using histological and histomorphometric analysis.Tissue engineering has been developing rapidly through the use of various biomaterials for the treatment of bone defects, such as mechanical barriers consisting of biological membranes and implants of biomaterials for bone supply.Thirty-two male rats were divided into four groups (n = 8): group I-C: control; group II-PT: photobiomodulation therapy; group III-PM: Gen-ProHistological analysis confirmed the histomorphometric results, with the experimental groups showing bone neoformation of significantly higher quality and quantity at the end of 30 days compared with the control group.Photobiomodulation therapy was effective for bone repair mainly when associated with BMPs and a biological membrane. The results of this study are promising and stimulate further scientific and clinical research. |
| Databáze: | OpenAIRE |
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