Selected Sulfhydryl Inhibitors Capable of Inducing Immunity against Cancer in Mice
| Autor: | Knock Fe, R. Sylvester, H. Rebechini-Zasadny, Galt Rm, Oester Yt |
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| Rok vydání: | 1979 |
| Předmět: |
Drug
Cancer Research Organomercury Compounds media_common.quotation_subject Iodoacetates Pharmacology Biology Arsenicals Mice Immunity medicine Animals Neoplasm Carcinoma Ehrlich Tumor media_common Microvilli Sulfhydryl Reagents food and beverages Cancer General Medicine medicine.disease Oncology Toxicity Immunology Microscopy Electron Scanning |
| Zdroj: | Oncology. 36:197-201 |
| ISSN: | 1423-0232 0030-2414 |
| DOI: | 10.1159/000225341 |
| Popis: | Selected sulfhydryl inhibitors show greater toxicity to some animal and human cancers than to normal cells, both clinically and in drug sensitivity tests. Such selected SH inhibitors can induce immunity against cancer in mice, unlike other commonly used antitumor agents. Scanning electron micrographs of the surface of Ehrlich ascites cancer cells treated with the sulfhydryl inhibitors show blunting to absence of microvilli and modification of the surface texture of the cancer cells. |
| Databáze: | OpenAIRE |
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