Supplemental Figure S3 from On-Target Effect of FK866, a Nicotinamide Phosphoribosyl Transferase Inhibitor, by Apoptosis-Mediated Death in Chronic Lymphocytic Leukemia Cells
| Autor: | Versha Banerji, Spencer B. Gibson, James B. Johnston, Armando G. Poeppl, Sara Beiggi, Eric D.J. Bouchard, Iris Gehrke |
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| Rok vydání: | 2023 |
| DOI: | 10.1158/1078-0432.22454565.v1 |
| Popis: | Figure S3: Cells were treated for one, two or three days with FK866 at 1 nM, 10 nM and 50 nM. A) AMPK was phosphorylated at all concentrations at day 1, but only at 1 nM after three days incubation with FK866. B) mTOR was phosphorylated at 1 nM and 10 nM FK866 at day 2. C) Erk1/2 was phosphorylated at 1 nM FK866 at day 2. Vinculin served as loading control. Ctrl: vehicle control |
| Databáze: | OpenAIRE |
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