Comparison of left side or right side vagotomy in the rat subjected to acute pancreatitis
| Autor: | Szklarczyk, Joanna, Kot, Michalina, Bonior, Joanna, Śliwowski, Zbigniew, Tomaszewska, Romana, Jaworek, Jolanta |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Caerulein induced pancreatitis Vagotomy Gastroenterology 03 medical and health sciences Pancreatic blood flow 0302 clinical medicine Internal medicine Edema Malondialdehyde Medicine Serum lipase Animals 030212 general & internal medicine Rats Wistar Pancreas Aldehydes business.industry Pancreatic tissue General Medicine Lipase Organ Size medicine.disease Interleukin-10 Pancreatitis Regional Blood Flow 030220 oncology & carcinogenesis Acute Disease Acute pancreatitis medicine.symptom business |
| Zdroj: | Advances in medical sciences. 64(1) |
| ISSN: | 1898-4002 |
| Popis: | PURPOSE We aimed to evaluate the effects of unilateral vagotomy (right-VR or left-VL) on the severity of caerulein-induced acute pancreatitis (AP). MATERIAL AND METHODS VR or VL was done in Wistar rats 4 days before AP, except in control, sham operated group. Following 5 h administration of subcutaneous injections of caerulein, the pancreatic blood flow (PBF), serum lipase and IL-10 in caval blood samples were measured. The pancreatic specimens were taken from sacrificed rats for the assessment of MDA-4-HNE and morphology. RESULTS PBF decreased from 310 ± 20 ml/min/100 g of tissue in control rats to 130 ± 12 units in AP (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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