Synthesis of fused imidazo-pyridine and -azepine derivatives by sequential van Leusen/Heck reactions

Autor:	Vijaya Gracias, Xenia Beebe, Stevan W. Djuric
Rok vydání:	2006
Předmět:	Molecular complexity chemistry.chemical_compound Chemistry Intramolecular force Organic Chemistry Drug Discovery Pyridine Organic chemistry General Medicine Azepine Biochemistry Combinatorial chemistry
Zdroj:	Tetrahedron Letters. 47:3225-3228
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2006.03.056
Popis:	Fused imidazo-pyridine and -azepine derivatives were synthesized using a sequential van Leusen/intramolecular Heck protocol. The combination of a multicomponent reaction followed by an intramolecular carbon–carbon bond forming reaction generates heterocycles of significant molecular complexity from readily available starting materials in just two steps.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4acfe3de62efbe31324fc26901c87ea5 https://doi.org/10.1016/j.tetlet.2006.03.056 Zobrazit plný text záznamu Full Text from ScienceDirect