Cell migration in the periodontal ligament of mice
| Autor: | A. H. Melcher, C. A. G. McCulloch |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Male
Molar education.field_of_study Time Factors Cell division Periodontal Ligament Population Mice Inbred Strains Cell migration Anatomy Biology Andrology Mice medicine.anatomical_structure Cell Movement Labelling medicine Animals Autoradiography Periodontics Periodontal fiber Cementum education Cell Division Dental alveolus |
| Zdroj: | Journal of Periodontal Research. 18:339-352 |
| ISSN: | 1600-0765 0022-3484 |
| DOI: | 10.1111/j.1600-0765.1983.tb00369.x |
| Popis: | Cell migration and the rate at which cells divide was examined in the periodontal ligament of mouse molars. A pulse injection of 3H-Tdr was administered, and mice were sacrificed between 1 hour and 60 days after injection. Analysis of radioautographs using labelling index and grain counts demonstrated that the majority of labelled cells divided within 3 days but a measurable population of cells had not divided after 14 days. These cells were G2-blocked. The labelling index of cells adjacent to alveolar bone increased 8 times within 1 day, indicating that labelled cells had migrated to the bone surface. Migration of cells to the vicinity of the cementum was observed 3 days after labelling. The percentage of labelled cells located within 20μm of one another increased to 40% within 3 days, suggesting clonal proliferation of periodontal ligament cells. |
| Databáze: | OpenAIRE |
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