An injectable dosimeter for small animal irradiations
| Autor: | Guy Garty, David J. Brenner, Monica Pujol-Canadell |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
Materials science Physics - Instrumentation and Detectors FOS: Physical sciences Radiation In Vivo Dosimetry Radiation Dosage Article 030218 nuclear medicine & medical imaging 03 medical and health sciences Mice 0302 clinical medicine In vivo Radiation Monitoring Small animal Dosimetry Animals Radiology Nuclear Medicine and imaging Irradiation Dosimeter Radiological and Ultrasound Technology Radiation Dosimeters Radiation field Instrumentation and Detectors (physics.ins-det) Physics - Medical Physics Mice Inbred C57BL 030220 oncology & carcinogenesis Medical Physics (physics.med-ph) Thermoluminescent dosimeter Biomedical engineering |
| Zdroj: | Phys Med Biol |
| Popis: | Accuracy and precision in dosimetry is crucial in studies involving animal models. Small animal dosimetry, in particular for protracted exposures to non uniform radiation fields is particularly challanging. We have developed a novel in vivo dosimeter based on glass encapsulated TLD rods. These encapsulated rods can be injected into mice and used for validating doses to an individual mouse in a protracted irradiation scenario where the mouse is free to move in an inhomogenous radiation field. Data from 30 irradiated mice shows a reliable dose reconstruction within 10% of the nominal delivered dose. |
| Databáze: | OpenAIRE |
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