Rigid Mn(ii) chelate as efficient MRI contrast agent for vascular imaging
| Autor: | Hongying Su, Dan Wang, Hua Ai, Jiang Zhu, Chunchao Xia, Tianxin Miao, Xuna Zhao, Bin Song, Qiyong Gong, Changqiang Wu |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Pyridines
MRI contrast agent Molecular Conformation Contrast Media Crystallography X-Ray Veins Inorganic Chemistry chemistry.chemical_compound Nuclear magnetic resonance Piperidines Coordination Complexes Pyridine medicine Humans Chelation Chelating Agents Manganese Vascular imaging medicine.diagnostic_test Ligand Magnetic resonance imaging Crown Compounds Magnetic Resonance Imaging chemistry Piperidine Signal intensity |
| Zdroj: | Dalton Transactions. 41:14480 |
| ISSN: | 1477-9234 1477-9226 |
| Popis: | The aza-semi-crown pentadentate ligand rigidified by pyridine and piperidine rings was designed and synthesized. It can react with Mn(II) in water to form complex with improved longitudinal relaxivity, leading to efficient signal intensity enhancement of vascular vessels under a clinical magnetic resonance imaging scanner. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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