Longevity and Mortality Distributions of Mice With and Without X-Ray Exposure to 45 Generations of Male Progenitors

Autor:	Mary R. Brooks, J. F. Spalding
Rok vydání:	1972
Předmět:	Male Genetics Analysis of Variance Genotype Life span media_common.quotation_subject Longevity Mice Inbred Strains Biology X ray exposure General Biochemistry Genetics and Molecular Biology Mice Radiation Injuries Experimental Animals Radiation Genetics Progenitor cell Inbreeding media_common
Zdroj:	Experimental Biology and Medicine. 139:15-18
ISSN:	1535-3699 1535-3702
DOI:	10.3181/00379727-139-36066
Popis:	SummaryLongevity and mortality distributions were observed on two H-2 genotype substrains of mice within each of two lines. Two substrains (H-2f and H-2k) were from 45 generations of X-irradiated male progenitors, and two were from nonirradiated progenitors with the same degree of inbreeding. Lifespan differed significantly for H-2 genotypes within the two lines but not for the same genotypes between lines. It was concluded that life shortening was not a genetic consequence of 45 generations of exposure to over 4500 times the background radiation level. The data also suggest a single-gene effect on longevity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab9a06c4a9af4222cf5beda67d90662 https://doi.org/10.3181/00379727-139-36066 Zobrazit plný text záznamu