Hemorrhagic acneiform lesions in a teenager as the initial presentation of granulomatosis with polyangiitis
| Autor: | Erica Good, Elizabeth Alvarez-Connelly, Jasem Alshaiji, Jacquelyn Dosal, Santiago De Solo, Carlos Ricotti |
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| Rok vydání: | 2013 |
| Předmět: |
Vasculitis
Pathology medicine.medical_specialty Folliculitis Hemorrhage Dermatology Young Adult Biopsy Acne Vulgaris medicine Humans Young adult Age of Onset Sinusitis medicine.diagnostic_test business.industry Age Factors Granulomatosis with Polyangiitis medicine.disease Pediatrics Perinatology and Child Health Rituximab Female Granulomatosis with polyangiitis Granulomatous Dermatitis business Facial Dermatoses medicine.drug |
| Zdroj: | Pediatric dermatology. 31(1) |
| ISSN: | 1525-1470 |
| Popis: | A 19-year-old girl presented with hemorrhagic acneiform lesions on the face for several months that was unresponsive to conventional acne treatment. A biopsy revealed a noninfectious suppurative granulomatous dermatitis with hemorrhage, possibly representing a ruptured folliculitis. A second biopsy revealed chronic granulomatous dermal inflammation and hemorrhage with foreign body giant cells non-infectious by stains. No vasculitis was noted in either biopsy. Later in her course she developed a severe sinusitis and eventually presented with severe fevers, rapid weight loss, sinusitis, and cough. Further workup produced the diagnosis of granulomatosis with polyangiitis (Wegener's granulomatosis). She rapidly improved with intravenous steroids and rituximab. To date, acneiform lesions have only been reported in young adult patients and may represent a clinical manifestation of granulomatosis with polyangiitis unique to this age group, as illustrated in our patient. |
| Databáze: | OpenAIRE |
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