First whole genome characterization of swine influenza virus subtype H3N2 in Thailand
| Autor: | Wilairat Chumsing, Worawidh Wajjwalku, Richard J. Webby, Jinpanee Nanakorn, Porntippa Lekcharoensuk |
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| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
Swine animal diseases viruses Molecular Sequence Data Orthomyxoviridae Genome Viral Biology medicine.disease_cause Microbiology H5N1 genetic structure Genome Virus Orthomyxoviridae Infections Molecular genetics Pandemic medicine Influenza A virus Animals Gene Phylogeny Swine Diseases Base Sequence General Veterinary Reverse Transcriptase Polymerase Chain Reaction Influenza A Virus H3N2 Subtype virus diseases Sequence Analysis DNA General Medicine Thailand biology.organism_classification Virology Cross-Sectional Studies RNA Viral |
| Zdroj: | Veterinary Microbiology. 145:230-244 |
| ISSN: | 0378-1135 |
| Popis: | H3N2 swine influenza viruses (SIV) were first detected in Asia shortly after the 1968 pandemic emerged in humans. Subsequently, human H3N2 viruses have sporadically reappeared in swine. In Thailand, a human-like H3N2 SIV was reported in 1978 although the genetic sequence of this virus is unknown. In this study, we undertook cross sectional syndromic surveillance in pigs in four provinces in Thailand. Seven genetically similar H3N2 viruses were isolated. A representative, A/SW/Thailand/KU5.1/04, was fully sequenced and shown to contain genes from human-like influenza viruses and North American and European SIV. The results restate that transmission of influenza A virus among human and swine populations is common and that genes from both American and Eurasian SIV lineages cocirculate in Thailand. |
| Databáze: | OpenAIRE |
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