An experimental rat model of electric shock injury with isolated electric shock and water conduction: the histopathological changes on the skin and internal organs and the effect on biochemical parameters

Autor: Ahmet Sedat Dündar, Mucahit Oruç, Osman Celbiş, Emine Türkmen Şamdancı, Ayşe Nur Akatlı, Hasan Okumuş, Çağatay Taşkapan, Onural Özhan, Hakan Parlakpınar
Rok vydání: 2022
Předmět:
Zdroj: International Journal of Legal Medicine. 137:215-226
ISSN: 1437-1596
0937-9827
Popis: It is difficult to determine the cause of death in electric shock injuries when no trace can be determined on the skin, and this is accepted as a reason for negative autopsy. We aimed to determine useful parameters in the definition of the cause of deaths associated with electric shock and particularly those formed with water conduction. This study used a total of 42 rats, applied with fatal electric shock formed of isolated electric shock at 220 V and with water conduction. The serum NT-ProBNP and H-FABP levels were examined together with histopathological changes in the brain, cerebellum, brainstem, heart, liver and skin and the Bax, caspase-3 and HSP-60 antibody status in these tissues. A statistically significant difference was determined between the groups in respect of the serum H-FABP values and the immunohistochemical staining of the samples taken from the organs. In conclusion, this study is the first in literature with an experimental model of electric shock with water conduction. Using immunohistochemical and biochemical markers in deaths associated with isolated electric shock and electric shock with water conduction, the results of this study can contribute to the clarification of one of the reasons for negative autopsy in forensic medicine.
Databáze: OpenAIRE
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