Access to Both Anomers of Pectenotoxin Spiroketals by Kinetic Spiroketalization

Autor:	Petri M. Pihko, Jatta E. Aho
Rok vydání:	2004
Předmět:	Magnetic Resonance Spectroscopy Anomer Molecular Structure Stereochemistry Chemistry Organic Chemistry Ring (chemistry) Kinetic energy Biochemistry Catalysis Marine Toxins Physical and Theoretical Chemistry Chirality (chemistry) Pyrans
Zdroj:	Organic Letters. 6:3849-3852
ISSN:	1523-7052 1523-7060
DOI:	10.1021/ol048321t
Popis:	[structure: see text] A concise synthesis of both AB ring spiroisomers of the pectenotoxins is described. The nonanomeric AB spiroketal ring system of the pectenotoxins-1, -2, -3, and -6 is formed under very mild, kinetic spiroketalization conditions, along with the anomeric isomer. Only catalytic asymmetric transformations were used as the source of chirality in the synthesis route.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aae56dd61edb73a600e3b991ebe07fd https://doi.org/10.1021/ol048321t Zobrazit plný text záznamu