Bifidobacteria inhibit the growth ofPorphyromonas gingivalisbut not ofStreptococcus mutansin an in vitro biofilm model
| Autor: | Akihito Endo, Heli Jäsberg, Anna Haukioja, David Beighton, Eva Söderling |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Bifidobacterium longum Gingiva digestive system Microbiology Streptococcus mutans 03 medical and health sciences fluids and secretions 0302 clinical medicine Humans General Dentistry Bifidobacterium ta313 Fusobacterium nucleatum biology Biofilm food and beverages 030206 dentistry biology.organism_classification Bifidobacterium dentium Bifidobacterium animalis stomatognathic diseases 030104 developmental biology Biofilms Actinomyces naeslundii bacteria Porphyromonas gingivalis |
| Zdroj: | European Journal of Oral Sciences. 124:251-258 |
| ISSN: | 0909-8836 |
| DOI: | 10.1111/eos.12266 |
| Popis: | There is growing interest in the use of probiotic bifidobacteria for enhancement of the therapy, and in the prevention, of oral microbial diseases. However, the results of clinical studies assessing the effects of bifidobacteria on the oral microbiota are controversial, and the mechanisms of actions of probiotics in the oral cavity remain largely unknown. In addition, very little is known about the role of commensal bifidobacteria in oral health. Our aim was to study the integration of the probiotic Bifidobacterium animalis subsp. lactis Bb12 and of oral Bifidobacterium dentium and Bifidobacterium longum isolates in supragingival and subgingival biofilm models and their effects on other bacteria in biofilms in vitro using two different in vitro biofilms and agar-overlay assays. All bifidobacteria integrated well into the subgingival biofilms composed of Porphyromonas gingivalis, Actinomyces naeslundii, and Fusobacterium nucleatum and decreased significantly only the number of P. gingivalis in the biofilms. The integration of bifidobacteria into the supragingival biofilms containing Streptococcus mutans and A. naeslundii was less efficient, and bifidobacteria did not affect the number of S. mutans in biofilms. Therefore, our results suggest that bifidobacteria may have a positive effect on subgingival biofilm and thereby potential in enhancing gingival health; however, their effect on supragingival biofilm may be limited. |
| Databáze: | OpenAIRE |
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