IMMUNOLOGIC DYSFUNCTION IN CANCER

Autor: Denise Kavanaugh, David P. Carbone
Rok vydání: 1996
Předmět:
Zdroj: Hematology/Oncology Clinics of North America. 10:927-952
ISSN: 0889-8588
DOI: 10.1016/s0889-8588(05)70376-2
Popis: The interactions between the tumor and its host are complex, and many aspects of the immune system appear to be adversely affected directly or indirectly by the presence of the tumor. Virtually all of the processes involved in immune induction and action have been implicated in the observed deficient response in tumor-bearing patients. Improved understanding and molecular analysis of the mechanisms underlying the escape of tumors from immune surveillance may lead to the development of novel strategies for the prevention of T-cell immunosuppression in cancer patients, the development of novel immunotherapeutic strategies, and potentially prevention of tumor progression or development.
Databáze: OpenAIRE