Female genital tract chronic graft-versus-host disease: A narrative review

Autor: Morgani Rodrigues, Andréa Maria Novaes Machado, Lenira Maria Queiroz Mauad, Carla de Azevedo Piccinato, Nelson Hamerschlak, Sergio Podgaec
Rok vydání: 2019
Předmět:
Zdroj: Hematology, Transfusion and Cell Therapy, Volume: 41, Issue: 1, Pages: 69-75, Published: 15 APR 2019
Hematology, Transfusion and Cell Therapy
Hematology, Transfusion and Cell Therapy, Vol 41, Iss 1, Pp 69-75 (2019)
ISSN: 2531-1379
DOI: 10.1016/j.htct.2018.06.005
Popis: Graft-versus-host disease is one of the main causes of morbidity and mortality in patients submitted to hematopoietic stem cell transplantation. This study reviewed the prevalence of lower female genital tract graft-versus-host disease following hematopoietic stem cell transplantation. A systematic search of the literature for articles published between 1982 and 2015 was performed. A growing number of young women suffering from malignant and benign hematological diseases are receiving allogeneic hematopoietic stem cell transplantation with very satisfactory results in relation to the disease itself. However, these patients face gynecological problems due to graft-versus-host disease. Correct diagnosis and early management are needed to avoid irreversible complications. Keywords: Graft-versus-host disease, Hematopoietic stem cell transplantation, Gynecology, Cancer treatment
Databáze: OpenAIRE