Preoperative Gabapentin Administration and Its Impact on Postoperative Opioid Requirement and Pain in Sinonasal Surgery
| Autor: | Machelle D. Wilson, Amarbir S. Gill, Joshua C. Hwang, Farrukh R. Virani, Angela M. Beliveau, E. Bradley Strong, Toby O. Steele |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Gabapentin Chronic rhinosinusitis Visual analogue scale Postoperative pain 03 medical and health sciences 0302 clinical medicine Preoperative Care medicine Humans Sinusitis 030223 otorhinolaryngology Aged Retrospective Studies Rhinitis Analgesics Pain Postoperative business.industry Chronic pain Middle Aged medicine.disease Surgery Analgesics Opioid Treatment Outcome Otorhinolaryngology Migraine Opioid Chronic Disease Female business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 164(4) |
| ISSN: | 1097-6817 |
| Popis: | To determine the efficacy of preoperative gabapentin on patient-reported pain levels and postoperative opioid requirements following sinonasal surgery.Retrospective review.Academic institution.Patients undergoing sinonasal surgery between July 2019 and January 2020 were followed. Groups were divided into those that received 600 mg of oral gabapentin 1 hour preoperatively (gabapentin) and those that did not (control). Postoperatively, each patient was counseled to use acetaminophen, ibuprofen, and oxycodone as needed for pain control. Patients completed a daily postoperative pain and medication log. Pain was measured by the visual analog scale (VAS) and opioid use by morphine equivalent dose (MED). Chi-square test and Wilcoxon test were used for data analysis.Fifty-seven patients were included (control, n = 28; gabapentin, n = 29). There was no significant difference in age, sex, or baseline Sinonasal Outcome Test-22 scores between the groups. The total MED, postoperative day (POD) 1-2 MED, POD 3-4 MED, and POD 5-6 MED did not differ significantly between the control (17.9, 12.2, 4.6, 1.5) and gabapentin (19.0, 8.9, 7.2, 3.5) groups (Preoperative gabapentin did not significantly reduce postoperative pain or opioid use. Postoperative discomfort following sinonasal surgery is mild, and opioid intake is minimal. |
| Databáze: | OpenAIRE |
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