Passage of bracken fern toxicity into milk
| Autor: | R. S. Jones, I A Evans, R. Mainwaring-Burton |
|---|---|
| Rok vydání: | 1972 |
| Předmět: |
Blood Platelets
Bone Marrow Cells Bone Marrow Aplasia Microbiology chemistry.chemical_compound Leukocyte Count Mice Pregnancy Botany Animals Lactation Carcinogen Toxins Biological Plant Poisoning Multidisciplinary biology Plant Extracts biology.organism_classification Milk chemistry Hematocrit Toxicity Carcinogens Pteridium aquilinum Cattle Female Fern Bracken Ptaquiloside |
| Zdroj: | Nature. 237(5350) |
| ISSN: | 0028-0836 |
| Popis: | BRACKEN (Pteridium aquilinum) and extracts of the plant have pluripotent carcinogenic and mutagenic properties, and if administered in sufficient concentration are acutely toxic to species as varied as mice and bovines1–9. The causative factor(s) of these different biological activities seem to be identical; they are produced by the same purified fraction although obtained by different fractionation procedures5,10–12. This is not surprising because the acute lethal syndrome is radiomimetic in nature, being characterized by bone marrow aplasia, haemorrhage and severe gastro-intestinal damage, together with other systemic changes common to both syndromes13–15. |
| Databáze: | OpenAIRE |
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