Dose and dose rate effectiveness of space radiation
| Autor: | W. Schimmerling, F. A. Cucinotta |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Work (thermodynamics)
Radiation Radiation Dosage Models Biological Risk Assessment Animals Humans Radiology Nuclear Medicine and imaging Computer Simulation Radiation Injuries Physics End point Radiological and Ultrasound Technology business.industry Public Health Environmental and Occupational Health Dose-Response Relationship Radiation General Medicine Space radiation Weighting Radiation exposure Particle type Body Burden Biological system Dose rate Nuclear medicine business Cosmic Radiation Relative Biological Effectiveness |
| Zdroj: | Radiation protection dosimetry. 122(1-4) |
| ISSN: | 0144-8420 |
| Popis: | Dose and dose rate effectiveness factors (DDREF), in conjunction with other weighting factors, are commonly used to scale atomic bomb survivor data in order to establish limits for occupational radiation exposure, including radiation exposure in space. We use some well-known facts about the microscopic pattern of energy deposition of high-energy heavy ions, and about the dose rate dependence of chemical reactions initiated by radiation, to show that DDREF are likely to vary significantly as a function of particle type and energy, cell, tissue, and organ type, and biological end point. As a consequence, we argue that validation of DDREF by conventional methods, e.g. irradiating animal colonies and compiling statistics of cancer mortality, is not appropriate. However, the use of approaches derived from information theory and thermodynamics is a very wide field, and the present work can only be understood as a contribution to an ongoing discussion. |
| Databáze: | OpenAIRE |
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