Hair cortisol concentrations exhibit a positive association with salivary cortisol profiles and are increased in obese prepubertal girls
| Autor: | Papafotiou, C., Christaki, Eirini, Akker, E. L. T. van den, Wester, V. L., Apostolakou, Filia, Papassotiriou, Y., Chrousos, George P., Pervanidou, P. |
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| Přispěvatelé: | Pediatrics, Internal Medicine, Christaki, Eirini [0000-0002-8152-6367], Chrousos, George P. [0000-0002-3098-5264] |
| Rok vydání: | 2017 |
| Předmět: |
Saliva
medicine.medical_specialty endocrine system Hydrocortisone Physiology 030209 endocrinology & metabolism Salivary cortisol Childhood obesity Body Mass Index 03 medical and health sciences Behavioral Neuroscience 0302 clinical medicine Internal medicine Hair cortisol medicine Humans Obesity Child Inflammation integumentary system Endocrine and Autonomic Systems business.industry Body Weight medicine.disease Metabolic syndrome Psychiatry and Mental health Neuropsychology and Physiological Psychology Endocrinology medicine.anatomical_structure Cross-Sectional Studies Blood chemistry Hypothalamic-pituitary-adrenal axis Female business Body mass index 030217 neurology & neurosurgery Hypothalamic–pituitary–adrenal axis hormones hormone substitutes and hormone antagonists Hormone Hair |
| Zdroj: | Stress. The International Journal on the Biology of Stress, 20(2), 217-222. Informa Healthcare Stress |
| ISSN: | 1025-3890 |
| Popis: | Cortisol, a key mediator of the stress response, has been associated with obesity and metabolic syndrome manifestations as early as in childhood. Scalp hair cortisol has been proposed as a reliable index of long-term circulating cortisol. We aimed to investigate whether obese prepubertal girls have higher scalp hair cortisol than normal-weight controls and whether hair cortisol levels are correlated with salivary cortisol concentrations in these groups. In this cross-sectional study, 25 obese girls and 25 normal-weighted, age-matched girls were enrolled. Anthropometric evaluation, blood chemistry and salivary cortisol measurements were performed, and body mass index (BMI) and areas under the curve with respect to ground (AUCg) were calculated. Hair cortisol determination was performed with liquid chromatography–tandem mass spectrometry. Both hair cortisol concentrations and salivary cortisol AUCs were higher in the obese than the normal-weight girls (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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