Treatment of intracranial ependymoma by surgery alone
| Autor: | Dan Lefton, Fred Epstein, Juliette Hukin, Jeffrey C. Allen |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Ependymoma
Adult Male medicine.medical_specialty Time Factors Adolescent medicine.medical_treatment Central nervous system disease Glioma medicine Humans Prospective Studies Prospective cohort study Child medicine.diagnostic_test business.industry Brain Neoplasms Magnetic resonance imaging General Medicine medicine.disease Magnetic Resonance Imaging Surgery Radiation therapy Clinical trial Child Preschool Pediatrics Perinatology and Child Health Intracranial ependymoma Female Neurology (clinical) Neoplasm Recurrence Local business |
| Zdroj: | Pediatric neurosurgery. 29(1) |
| ISSN: | 1016-2291 |
| Popis: | Objective: This study aimed to determine the safety of deferring radiotherapy in pediatric intracranial ependymoma following a radiographically confirmed gross total resection in patients with localized disease. Methods: Children over age 3 were recruited prospectively from 1990 to 1997, following a surgical impression and radiologic confirmation of a gross total resection of an intracranial ependymoma. Results: 10/32 cases of intracranial ependymomas were both eligible and gave consent. 7 remain free of disease without further intervention. 3 recurred, 2 were salvaged with surgery and radiotherapy, none died. Conclusions: Deferral of radiotherapy following gross total resection alone is a safe option in supratentorial ependymomas. The pattern of recurrence is usually local and patients may be salvaged with additional surgery with or without radiotherapy. |
| Databáze: | OpenAIRE |
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