Genetic Determinants for Metal Tolerance and Antimicrobial Resistance Detected in Bacteria Isolated from Soils of Olive Tree Farms
| Autor: | Antonio Gálvez, Elena Ortega, Mª José Grande, Nicolás Glibota |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Microbiology (medical) metal tolerance Tetracycline Genetic traits 030106 microbiology Biochemistry Microbiology Article 03 medical and health sciences Antibiotic resistance medicine Pharmacology (medical) antimicrobial resistance General Pharmacology Toxicology and Pharmaceutics Gene biology lcsh:RM1-950 biology.organism_classification Phenotype lcsh:Therapeutics. Pharmacology 030104 developmental biology Infectious Diseases olive farming Bacteria medicine.drug Antibiotic resistance genes |
| Zdroj: | Antibiotics Volume 9 Issue 8 Antibiotics, Vol 9, Iss 476, p 476 (2020) |
| ISSN: | 2079-6382 |
| DOI: | 10.3390/antibiotics9080476 |
| Popis: | Copper-derived compounds are often used in olive tree farms. In a previous study, a collection of bacterial strains isolated from olive tree farms were identified and tested for phenotypic antimicrobial resistance and heavy metal tolerance. The aim of this work was to study the genetic determinants of resistance and to evaluate the co-occurrence of metal tolerance and antibiotic resistance genes. Both metal tolerance and antibiotic resistance genes (including beta-lactamase genes) were detected in the bacterial strains from Cu-treated soils. A high percentage of the strains positive for metal tolerance genes also carried antibiotic resistance genes, especially for genes involved in resistances to beta-lactams and tetracycline. Significant associations were detected between genes involved in copper tolerance and genes coding for beta-lactamases or tetracycline resistance mechanisms. A significant association was also detected between zntA (coding for a Zn(II)-translocating P-type ATPase) and tetC genes. In conclusion, bacteria from soils of Cu-treated olive farms may carry both metal tolerance and antibiotic resistance genes. The positive associations detected between metal tolerance genes and antibiotic resistance genes suggests co-selection of such genetic traits by exposure to metals. |
| Databáze: | OpenAIRE |
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