The Prevalence of unexpected antibodies in Saudi's plasma prior blood transfusion and their association with clinical conditions: A cross-sectional study
| Autor: | Yousif Mohammed Elmosaad, Ahmed Hattan Hattan, Faris Q. Alenzi, Hisham Ali Waggiallah, Maher M. Al-Enazi, Abdulkarim S. Bin Shaya |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0106 biological sciences
0301 basic medicine medicine.medical_specialty Blood transfusion QH301-705.5 Cross-sectional study medicine.medical_treatment 01 natural sciences 03 medical and health sciences Internal medicine ABO blood group system medicine Antibody identification Biology (General) Prospective cohort study Pregnancy biology business.industry Unexpected antibody medicine.disease Blood group 030104 developmental biology biology.protein Original Article Antibody General Agricultural and Biological Sciences business Rh blood group system 010606 plant biology & botany |
| Zdroj: | Saudi Journal of Biological Sciences Saudi Journal of Biological Sciences, Vol 28, Iss 8, Pp 4699-4703 (2021) |
| ISSN: | 2213-7106 1319-562X |
| Popis: | Unexpected antibodies, also called irregular antibodies, are not known to exist in a person’s serum before testing. This research aims to assess the prevalence of unexpected antibodies and their correlation with several clinical conditions. This cross-sectional prospective study, undertaken from June 2019 to June 2020, included ABO, Rh grouping, cross-matching, and antibody screening. Antibody identification was performed only on patients who tested positive in the screening test. From a total of 9764 participants who were screened for unexpected antibodies, 107 (1.1%) tested positive. The Rh blood group system antibodies were the most frequent, particularly anti-D. There was also a significant correlation between the unexpected antibodies and history of transfusion, pregnancy, and autoimmune diseases as P 0.05. The most prominent unexpected antibodies in the study belong to the Rh system (Anti-D). Moreover, as a result of the strong correlation between the unexpected antibodies as well as the history of transfusion, pregnancy, and autoimmune diseases, the highest safety criteria must be followed during the transfusion of blood to patients with these clinical conditions. |
| Databáze: | OpenAIRE |
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