Prevalence of pre-diabetes and undiagnosed diabetes in the Mollerussa prospective observational cohort study in a semi-rural area of Catalonia

Autor: Esmeralda Castelblanco, Cristina Cebrian, Mireia Falguera, Àngels Molló, Nuria Alcubierre, Didac Mauricio, Josep Ramon Marsal, Neus Miró, Maria Belén Vilanova, Minerva Granado-Casas, Manel Mata-Cases, Josep Franch-Nadal
Rok vydání: 2020
Předmět:
Zdroj: BMJ Open
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Recercat. Dipósit de la Recerca de Catalunya
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Repositorio Abierto de la UdL
Universitad de Lleida
ISSN: 2044-6055
DOI: 10.1136/bmjopen-2019-033332
Popis: ObjectivesTo assess the prevalence of undiagnosed diabetes and pre-diabetes in the healthy population in the Mollerussa cohort. As a secondary objective, to identify the variables associated with these conditions and to describe the changes in glycaemic status after 1 year of follow-up in subjects with pre-diabetes.DesignProspective observational cohort study.SettingGeneral population from a semi-rural area.ParticipantsThe study included 583 participants without a diagnosis of diabetes recruited between March 2011 and July 2014.ResultsThe prevalence of undiagnosed diabetes was 20, 3.4% (95% CI 2.6 to 4.2) and that of pre-diabetes was 229, 39.3% (37.3 to 41.3). Among those with pre-diabetes, 18.3% had isolated impaired fasting plasma glucose (FPG) (FPG: 100 to ConclusionsAmong adults in our region, the estimated prevalence of undiagnosed diabetes was 3.4% and that of pre-diabetes was 39.3%. After a 1-year follow-up, a small proportion of subjects (0.6%) with pre-diabetes progressed to diabetes, while a high proportion (41.6%) returned to normoglycaemia. Individuals with pre-diabetes who returned to normoglycaemia were younger and had a lower body mass index.
Databáze: OpenAIRE