A homodienolate-enone addition
| Autor: | Chad C. Stessman, Vishwakarma Singh, Michael D. Carducci, S. Prathap, Sanjoy Lahiri, Vinayak V. Kane, Robert B. Bates |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2000 |
| Předmět: | |
| Zdroj: | IndraStra Global. |
| ISSN: | 2381-3652 |
| Popis: | On treatment with sodium hydride, a mixture of ketone 1 and enone 4 gives a 48% yield of adduct 2, which contains two new carbon-carbon bonds. The reaction very likely involves homodienolate 3, which may either undergo a Michael addition or a cycloaddition to enone 4 to give intermediate adduct 6 or 7, respectively. Adduct 6 may then undergo homo-Michael addition to give adduct 7. Cyclopropane ring-opening of adduct 7 and protonation give the observed adduct 2. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|