Severe headache in primary Sjögren’s syndrome treated with intrathecal rituximab

Autor:	Katrine Brække Norheim, Anne Bolette Tjensvoll, Maria B. Lauvsnes, Roald Omdal
Rok vydání:	2019
Předmět:	medicine.medical_specialty Severe headache lcsh:Medicine Case Report Primary Sjögren’s syndrome Case Reports Triptans 030204 cardiovascular system & hematology Intrathecal Pathogenesis 03 medical and health sciences Systemic lupus erythematosus 0302 clinical medicine medicine lcsh:R5-920 business.industry lcsh:R Headache B cell depletion in CSF General Medicine Dermatology 030220 oncology & carcinogenesis Rituximab Sjogren s lcsh:Medicine (General) business medicine.drug
Zdroj:	Clinical Case Reports Clinical Case Reports, Vol 7, Iss 3, Pp 416-418 (2019)
ISSN:	2050-0904
Popis:	Key Clinical Message A severe and persistent migrainous headache in a patient with primary Sjøgren's syndrome unresponsive to treatment with immunosuppressive drugs, triptans, opioids, and NSAIDs, responded successfully to intrathecal B‐cell depletion with rituximab. We hypothesize that brain‐resident autoreactive B cells were involved in headache pathogenesis and were eliminated by this procedure.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a7e26dc310d982724dbbbc7f2ade4f0 https://doi.org/10.1002/ccr3.1987 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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