A new β-class milbemycin derivative from a mutant of genetically engineered strain Streptomyces avermitilis AVE-H39
| Autor: | Huan Qi, Li-Qin Zhang, Wensheng Xiang, Wen-Shuai Song, Shao-Yong Zhang, Cheng-Hong Zhang, Ji-Dong Wang |
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| Rok vydání: | 2021 |
| Předmět: |
biology
Chemistry Genetically engineered Stereochemistry Strain (biology) Organic Chemistry Mutant Absolute configuration Plant Science biology.organism_classification Biochemistry Analytical Chemistry Milbemycin chemistry.chemical_compound Fermentation broth Streptomyces avermitilis Derivative (chemistry) |
| DOI: | 10.6084/m9.figshare.16775875.v1 |
| Popis: | A new β-class milbemycin, 13α-hydroxy milbemycin β6 (1), was isolated from the fermentation broth of a mutant of genetically engineered strain Streptomyces avermitilis AVE-H39. Its structure and absolute configuration were elucidated by extensive spectroscopic methods and confirmed by single crystal X-ray diffraction. |
| Databáze: | OpenAIRE |
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