Antibiotic Resistance Profile and Biofilm Production of Staphylococcus pseudintermedius Isolated from Dogs in Thailand
| Autor: | Dennapa Saeloh, Hawaree Heemmamad, Jongkon Saising, Saowakon Indoung, Tanawan Soimala, Pavarish Jantorn, Julalak Chokpaisarn, Varomyalin Tipmanee, Warapond Wanna |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Staphylococcus pseudintermedius antibiotic resistance Tetracycline 030106 microbiology Pharmaceutical Science Article biofilm Microbiology 03 medical and health sciences Pharmacy and materia medica Antibiotic resistance Drug Discovery medicine methicillin biology SCCmec Biofilm Clindamycin biochemical phenomena metabolism and nutrition biology.organism_classification Trimethoprim RS1-441 Ciprofloxacin 030104 developmental biology Medicine Molecular Medicine medicine.drug |
| Zdroj: | Pharmaceuticals Pharmaceuticals, Vol 14, Iss 592, p 592 (2021) Volume 14 Issue 6 |
| ISSN: | 1424-8247 |
| Popis: | Staphylococcus pseudintermedius is a zoonotic pathogen that can cause life-threatening infections in animals and humans. The study of methicillin-resistant S. pseudintermedius (MRSP) and its ability to produce biofilms is important to select the most suitable treatment. The prevalence and characteristics of S. pseudintermedius isolated from dogs admitted at the Veterinary Teaching Hospital, Prince of Songkla University, Thailand were assessed. Results showed that 28.30% (15/53) of the isolates were MRSP. Amplification of the mecA gene was observed in 93.33% (14/15) MRSP. Methicillin-resistant strains revealed co-resistant patterns against other antibiotics, including chloramphenicol, clindamycin, tetracycline, clarithromycin, ciprofloxacin, and trimethoprim. In this study, all bacterial isolates produced biofilms, while 90.55% of S. pseudintermedius isolates were strong or moderate biofilm producers. Most (45–60%) of the resistant strains were strong biofilm producers, while the correlation between biofilm production and antibiotic resistance was not statistically significant. This is the first study in southern Thailand to investigate the drug-resistant profile of S. pseudintermedius and its ability to form biofilm. The results will contribute to a better understanding of the emergence and prevalence of antimicrobial resistance in S. pseudintermedius. |
| Databáze: | OpenAIRE |
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