Assessing atropisomer axial chirality in drug discovery and development
| Autor: | Paul J. Edwards, Keith R. Fandrick, Oliver Hucke, Ray Kemper, Stephen P. F. Miller, Daniel R. Fandrick, Steven R. LaPlante, Lee Fader |
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| Rok vydání: | 2011 |
| Předmět: |
Models
Molecular Atropisomer Macrocyclic Compounds Stereochemistry Chemistry Drug discovery United States Food and Drug Administration Stereoisomerism Legislation Drug Amides Heterocyclic Compounds 4 or More Rings United States Structure-Activity Relationship Pharmaceutical Preparations Axial chirality Drug Discovery Molecular Medicine Thermodynamics Pharmacokinetics |
| Zdroj: | Journal of medicinal chemistry. 54(20) |
| ISSN: | 1520-4804 |
| Databáze: | OpenAIRE |
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