A C(Aryl)—N(Amine) Bond Atropisomeric Aminophosphine: Preparation and Use as a Ligand in a Catalytic Asymmetric Allylic Alkylation

Autor:	Daisuke Okumura, Youichi Tanaka, Toshihiro Yabusaki, Takashi Mino, Masami Sakamoto, Tsutomu Fujita
Rok vydání:	2003
Předmět:	Atropisomer Chemistry Stereochemistry Ligand Aryl Organic Chemistry General Medicine Medicinal chemistry Catalysis Inorganic Chemistry Chiral column chromatography chemistry.chemical_compound Tsuji–Trost reaction Amine gas treating Physical and Theoretical Chemistry Phosphine
Zdroj:	ChemInform. 34
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200352100
Popis:	The existence of 3 as a pair of stable atropisomers has been demonstrated analytically through chiral phase LC–CD investigations. Resolution of 3d was achieved by preparative chiral HPLC. Finally, the ability of the first C(aryl)N(amine) axially chiral phosphine ligand 3d is demonstrated in a catalytic asymmetric reaction.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a7071a141ee780a4df1514b3b23d906 https://doi.org/10.1002/chin.200352100 Zobrazit plný text záznamu Plný text