Ring-Closing Metathesis Reactions on Azinium Salts: Straightforward Access to Quinolizinium Cations and Their Dihydro Derivatives

Autor:	Ana M. Cuadro, Beatriz Abarca, Julio Alvarez-Builla, Ana Nunez, Juan J. Vaquero
Rok vydání:	2009
Předmět:	Solvent Grubbs' catalyst chemistry.chemical_compound Ring-closing metathesis Pyridinium Compounds Chemistry Organic Chemistry Salt metathesis reaction Organic chemistry Metathesis Chemical synthesis Catalysis
Zdroj:	The Journal of Organic Chemistry. 74:4166-4176
ISSN:	1520-6904 0022-3263
DOI:	10.1021/jo900292b
Popis:	The ring-closing metathesis reaction of 1-butenyl-2-vinylpyridinium salts and 2-butenyl-1-vinylpyridinium salts using Grubbs second generation and Hoveyda-Grubbs catalysts proved to be an efficient approach to 3,4-dihydro- and 1,2-dihydroquinolizinium salts and the corresponding quinolizinium derivatives by an improved thermal oxidation in the presence of Pd/C without solvent. A comparative study showed that the quinolizinium system was obtained in better yields through the 3,4-dihydroquinolizinium route, thus allowing the synthesis of quinolizinium derivatives or improvements in the yields of some examples reported previously.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a6ec6c9d47223c4a5c849d7172c00da https://doi.org/10.1021/jo900292b Zobrazit plný text záznamu