Significant Association Between Coronary Artery Low-Attenuation Plaque Volume and Apnea-Hypopnea Index, But Not Muscle Sympathetic Nerve Activity, in Patients With Obstructive Sleep Apnea Syndrome
| Autor: | Shinichiro Takashima, Soichiro Usui, Masayuki Takamura, Hisayoshi Murai, Shuichi Kaneko, Yoshitaka Okabe, Shigeo Takata, Takuto Hamaoka, Soichiro Kashiwaya, Hiroshi Furusho, Yu Sugiyama, Hiroyuki Sugimoto, Yasuto Nakatsumi, Hideki Tokuhisa, Takeshi Kato, Yusuke Mukai, Oto Inoue |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Sympathetic Nervous System Polysomnography Coronary Artery Disease 030204 cardiovascular system & hematology Coronary Angiography medicine.disease_cause 03 medical and health sciences 0302 clinical medicine stomatognathic system Internal medicine Plaque volume Humans Medicine In patient Aged Sleep Apnea Obstructive business.industry Sympathetic nerve activity General Medicine Middle Aged Coronary computed tomography medicine.disease Vulnerable plaque Plaque Atherosclerotic nervous system diseases respiratory tract diseases Obstructive sleep apnea medicine.anatomical_structure Apnea–hypopnea index Cardiology Female Tomography X-Ray Computed Cardiology and Cardiovascular Medicine business 030217 neurology & neurosurgery Artery |
| Zdroj: | Circulation Journal. 82:2852-2860 |
| ISSN: | 1347-4820 1346-9843 |
| DOI: | 10.1253/circj.cj-18-0237 |
| Popis: | BACKGROUND Obstructive sleep apnea syndrome (OSAS) is associated with augmented sympathetic nerve activity and cardiovascular diseases. However, the interaction between coronary artery plaque characteristics and sympathetic nerve activity remains unclear. The purpose of this study was to clarify the relationships between coronary artery plaque characteristics, sleep parameters and single- and multi-unit muscle sympathetic nerve activity (MSNA) in OSAS patients. Methods and Results: A total of 32 OSAS patients who underwent full-polysomnography participated in this study. The coronary plaque volume was calculated with 320-slice coronary computed tomography (CT). Single- and multi-unit MSNA were obtained during the daytime within 1 week from full-polysomnography. Patients were divided into 2 groups according to their apnea-hypopnea index (AHI) score (mild-moderate group, AHI |
| Databáze: | OpenAIRE |
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