Association between quality of life and various aspects of intradialytic hypotension including patient-reported intradialytic symptom score

Autor: Wim P. Krijnen, Wolter Paans, Carlo A. J. M. Gaillard, Casper F. M. Franssen, Ralf Westerhuis, Jurjen K. Oosterhuis, Johanna Kuipers
Přispěvatelé: Groningen Kidney Center (GKC), Nursing Diagnostics, Statistical Techniques for Applied Research
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Nephrology
Male
Quality of life
medicine.medical_specialty
medicine.medical_treatment
030232 urology & nephrology
Psychological intervention
Hemodynamics
030204 cardiovascular system & hematology
lcsh:RC870-923
Intradialytic hypotension
verpleegkunde
Cohort Studies
DEFINITIONS
03 medical and health sciences
0302 clinical medicine
nursing
Renal Dialysis
Diabetes mellitus
Internal medicine
Nursing Interventions Classification
Medicine
Humans
Prospective Studies
Dialysis
Aged
Netherlands
Aged
80 and over
business.industry
MORTALITY
Middle Aged
medicine.disease
lcsh:Diseases of the genitourinary system. Urology
Mental health
Patient reported outcome measures
Haemodialysis
Kidney Failure
Chronic
DIALYSIS-INDUCED HYPOTENSION
Female
Hypotension
business
SF-36 HEALTH SURVEY
kwaliteit van leven
Research Article
Zdroj: BMC Nephrology, Vol 20, Iss 1, Pp 1-8 (2019)
Bmc nephrology, 20(1):164. BMC
BMC Nephrology, 20(1). BioMed Central
BMC Nephrology
BMC Nephrology, 20(164). BioMed Central
ISSN: 1471-2369
Popis: Background There is increasing awareness that, besides patient survival, Quality of Life (QOL) is a relevant outcome factor for patients who have a chronic disease. In haemodialysis (HD) patients, intradialytic hypotension (IDH) is considered one of the most frequent complications, and this is often accompanied by symptoms. Several studies have investigated QOL in dialysis patients, however, research on the association between intradialytic symptoms and QOL is minimal. The goal of this study was to determine whether the occurrence of IDH has an influence on the perception of QOL. Methods During 3 months, haemodynamic data, clinical events, and interventions of 2623 HD-sessions from 82 patients were prospectively collected. The patients filled out a patient-reported intradialytic symptom score (PRISS) after each HD session. IDH was defined according to the EBPG as a decrease in SBP ≥20 mmHg or in MAP ≥10 mmHg associated with a clinical event and need for nursing interventions. Patient’s self-assessment of QOL was evaluated by the 36-Item Short-Form Health Survey. Results There were no significant associations between the mental summary score or the physical summary score and the proportion of dialysis sessions that fulfilled the full EBPG definition. A lower PRISS was significantly associated with the proportion of dialysis sessions that fulfilled the full EBPG definition (R = − 0.35, P = 0.0011), the proportion of dialysis sessions with a clinical event (R = − 0.64, P = 0.001), and the proportion of dialysis sessions with nursing interventions (R = − 0.41, P = 0.0001). The physical component summary and mental component summary were significantly negatively associated with the variable diabetes and positively with PRISS (P = 0.003 and P = 0.005, respectively). UF volume was significantly negatively associated with mental health (P = 0.02) and general health (P = 0.01). Conclusions Our findings suggest that the EBPG definition of IDH does not capture aspects of intradialytic symptomatology that are relevant for the patient’s QOL. In contrast, we found a significant association between QOL and a simple patient-reported intra-dialytic symptom score, implying that how patients experience HD treatment influences their QOL. Electronic supplementary material The online version of this article (10.1186/s12882-019-1366-2) contains supplementary material, which is available to authorized users.
Databáze: OpenAIRE
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