The role of contrast-enhanced ultrasound in the classification of CT-indeterminate renal lesions

Autor:	Geir Vegard Berg, Herzi Abdi Osman, Magne Dimmen, Kaja Gløersen, Jan Edenberg
Rok vydání:	2016
Předmět:	Adult Male medicine.medical_specialty Urology Contrast Media Computed tomography 030218 nuclear medicine & medical imaging Endosonography Lesion Diagnosis Differential 03 medical and health sciences 0302 clinical medicine medicine Humans Carcinoma Renal Cell Aged Aged 80 and over Kidney Incidental Findings medicine.diagnostic_test business.industry Cysts Ultrasound Mean age Middle Aged Kidney Neoplasms medicine.anatomical_structure Nephrology 030220 oncology & carcinogenesis Female Radiology Differential diagnosis medicine.symptom business Indeterminate Tomography X-Ray Computed Contrast-enhanced ultrasound
Zdroj:	Scandinavian journal of urology. 50(6)
ISSN:	2168-1813
Popis:	Focal renal lesions are common incidental findings on computed tomography (CT). For lesions with a cystic appearance, the Bosniak classification system has enabled an important separation of benign and (potentially) malignant cysts, giving a practical guide for management. The purpose of this study was to evaluate contrast-enhanced ultrasound (CEUS) as a problem-solving modality for classification of indeterminate renal lesions detected with CT.In total, 140 consecutive patients with 148 indeterminate renal lesions were examined with ultrasound combined with CEUS (81 men and 59 women with mean age 63.8 years).Altogether, 146 lesions were classified by CEUS in categories according to the Bosniak classification system, or as solid lesions. Mean lesion diameter was 30 mm (range 5-166 mm). Nine lesions were classified as category I, 32 as category II and 59 as category IIF ("non-surgical lesions"). 48 IIF cysts were followed for a minimum of 2 years (mean 4 years and 8 months): three lesions were upgraded to category III (6%) and 45 were stable category. 19 lesions had a more complex cystic appearance: 12 were classified as category III and seven as category IV cysts. 27 lesions were diagnosed as solid, enhancing tumors. In total, 25 patients with lesions of category III, IV and solid ("surgical lesions") underwent renal surgery, with malignancy diagnosed in 18.In the common setting of indeterminate renal lesions incidentally detected with a CT exam, CEUS has the potential to classify lesions into "non-surgical" and "surgical" categories, providing a platform for urological decision making, while avoiding radiation exposure.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a6214cee32e72fde60841c1d2fd4649 https://pubmed.ncbi.nlm.nih.gov/27609413 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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