UV-Crosslinked Electrospun Zein/PEO Fibroporous Membranes for Wound Dressing

Autor:	Medha Surendranath, Resmi Rajalekshmi, Rekha M. Ramesan, Prakash Nair, Ramesh Parameswaran
Rok vydání:	2022
Předmět:	Biomaterials Wound Healing Zein Biochemistry (medical) Biomedical Engineering Humans Collagen General Chemistry Fibroblasts Bandages
Zdroj:	ACS Applied Bio Materials. 5:1538-1551
ISSN:	2576-6422
DOI:	10.1021/acsabm.1c01293
Popis:	Electrospun zein membranes are suitable for various biomedical applications. A UV-crosslinked electrospun membrane of a zein/PEO blend for wound healing application was explored in this work. The improvement in mechanical properties of the membrane after UV crosslinking was attributed to the change in protein conformation from an α-helix to a β-sheet. The circular dichroism (CD) spectra and FTIR spectra confirmed this conformational change. XRD analysis was shown to prove the amorphous nature of polymer blends with specific broad peaks at 2θ = 9° and 20°. The water vapor transmission rate (WVTR) of the membrane was found to be in the range of 1500-2000 g m
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a60dcd6cb89315e546718c7b6945799 https://doi.org/10.1021/acsabm.1c01293 Zobrazit plný text záznamu