Role of ambulatory blood pressure monitoring in patients with acromegaly
Autor: | Adriana Martin, Roberta de Freitas Horn, Mauro Antonio Czepielewski, Fabiola Costenaro, Ticiana da Costa Rodrigues |
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Rok vydání: | 2016 |
Předmět: |
Adult
Male medicine.medical_specialty Ambulatory blood pressure Physiology Blood Pressure 030209 endocrinology & metabolism 030204 cardiovascular system & hematology Growth hormone Outpatient service 03 medical and health sciences 0302 clinical medicine Internal medicine Acromegaly Internal Medicine Humans Medicine In patient Insulin-Like Growth Factor I Aged Human Growth Hormone business.industry Blood Pressure Monitoring Ambulatory Middle Aged medicine.disease Blood pressure Echocardiography Hypertension Cohort Ambulatory Cardiology Female Cardiomyopathies Cardiology and Cardiovascular Medicine business |
Zdroj: | Journal of Hypertension. 34:1357-1363 |
ISSN: | 0263-6352 |
Popis: | Background Hypertension is associated with increased cardiovascular deaths in patients with acromegaly. Objective To evaluate the accuracy of blood pressure (BP) by 24-h ambulatory blood pressure monitoring (ABPM) and office BP measurements to represent the real BP status in acromegalic patients and its relationship with acromegalic activity and echocardiogram parameters. Patients and methods Cohort of 37 patients with acromegaly in a tertiary endocrine outpatient service. Results Twenty-three percent of the patients were considered hypertensive by ABPM versus 32% by office BP measurements (P = 0.006). BP obtained from the ABPM was associated with growth hormone, insulin-like growth factor type 1 levels and echocardiogram parameters of acromegalic myocardiopathy. Nondipper behavior presented a significant association with the hormonal profile. Conclusion BP levels assessed by ABPM were associated with acromegalic activity and echocardiogram parameters. ABPM can correctly identify BP levels and their repercussion on acromegalic patients. |
Databáze: | OpenAIRE |
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