Role of ambulatory blood pressure monitoring in patients with acromegaly

Autor: Adriana Martin, Roberta de Freitas Horn, Mauro Antonio Czepielewski, Fabiola Costenaro, Ticiana da Costa Rodrigues
Rok vydání: 2016
Předmět:
Zdroj: Journal of Hypertension. 34:1357-1363
ISSN: 0263-6352
Popis: Background Hypertension is associated with increased cardiovascular deaths in patients with acromegaly. Objective To evaluate the accuracy of blood pressure (BP) by 24-h ambulatory blood pressure monitoring (ABPM) and office BP measurements to represent the real BP status in acromegalic patients and its relationship with acromegalic activity and echocardiogram parameters. Patients and methods Cohort of 37 patients with acromegaly in a tertiary endocrine outpatient service. Results Twenty-three percent of the patients were considered hypertensive by ABPM versus 32% by office BP measurements (P = 0.006). BP obtained from the ABPM was associated with growth hormone, insulin-like growth factor type 1 levels and echocardiogram parameters of acromegalic myocardiopathy. Nondipper behavior presented a significant association with the hormonal profile. Conclusion BP levels assessed by ABPM were associated with acromegalic activity and echocardiogram parameters. ABPM can correctly identify BP levels and their repercussion on acromegalic patients.
Databáze: OpenAIRE