Fabrication of a Dipole-assisted Solid Phase Extraction Microchip for Trace Metal Analysis in Water Samples
| Autor: | I-Hsiang Hsu, Ming-Jay Deng, Sheng-Hao Tseng, Yang-Wei Lin, Ping-Hung Chen, Shun-Niang Chen, Tsung-Ting Shih, Yuh-Chang Sun |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Fabrication
Materials science Polymers Metal ions in aqueous solution General Chemical Engineering microchannel orientation Analytical chemistry Bioengineering Mass spectrometry Mass Spectrometry General Biochemistry Genetics and Molecular Biology Contact angle symbols.namesake Issue 114 dipole-assisted extraction Solid phase extraction trace metal analysis chemistry.chemical_classification General Immunology and Microbiology General Neuroscience Solid Phase Extraction Extraction (chemistry) Polymer Trace Elements chemistry Metals symbols microchip fabrication Raman spectroscopy polymer-based microchips |
| Zdroj: | Journal of Visualized Experiments : JoVE |
| ISSN: | 1940-087X |
| DOI: | 10.3791/53500-v |
| Popis: | This paper describes a fabrication protocol for a dipole-assisted solid phase extraction (SPE) microchip available for trace metal analysis in water samples. A brief overview of the evolution of chip-based SPE techniques is provided. This is followed by an introduction to specific polymeric materials and their role in SPE. To develop an innovative dipole-assisted SPE technique, a chlorine (Cl)-containing SPE functionality was implanted into a poly(methyl methacrylate) (PMMA) microchip. Herein, diverse analytical techniques including contact angle analysis, Raman spectroscopic analysis, and laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) analysis were employed to validate the utility of the implantation protocol of the C-Cl moieties on the PMMA. The analytical results of the X-ray absorption near-edge structure (XANES) analysis also demonstrated the feasibility of the Cl-containing PMMA used as an extraction medium by virtue of the dipole-ion interactions between the highly electronegative C-Cl moieties and the positively charged metal ions. |
| Databáze: | OpenAIRE |
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