Early detection of extended-spectrum β-lactamase from blood culture positive for an Enterobacteriaceae using βLACTA test

Autor: Antony Croxatto, Christian Durussel, Dominique S. Blanc, Guy Prod'hom, Gilbert Greub
Rok vydání: 2015
Předmět:
Zdroj: New Microbes and New Infections
New Microbes and New Infections, vol. 8, pp. 1-3
New Microbes and New Infections, Vol 8, Iss C, Pp 1-3 (2015)
ISSN: 2052-2975
DOI: 10.1016/j.nmni.2015.05.007
Popis: Bacterial pellets from Enterobacteriaceae positive blood cultures prepared using ammonium chloride were tested for rapid detection of β-lactamase using the commercial βLACTA test and read after 30 minutes. During 7 months, 137 bacterial pellets were tested prospectively. βLACTA test exhibited a sensitivity of 75% and a specificity of 100% for the detection of third-generation cephalosporin resistance. False negative tests were mainly observed with hyperproduced chromosomal or plasmid-borne AmpC.
Databáze: OpenAIRE